women at risk of breast cancer Refuses Preventative Drugs Due to Fear of Side Effects and ‘Fate’


Nearly nine out of 10 women reject a preventative treatment that could cut their risk of getting breast cancer because of a distrust of medications, fears about side-effects and a belief that the disease is down to “fate”, scientists have found.

Breast cancer drug tamoxifen has been recommended since 2013 for women with a high risk of developing breast cancer because of their family history, and can cut their chances of ever developing cancer by a third.

But a study by UK researchers found that six out of seven women turn down the treatment.

While women with children were more likely to take up tamoxifen, others felt that the menopause-like side effects could be too much to take on with no guarantee that they would stay cancer-free.

Interviews with a cross-section of the women who took part in the study asked for more detail about their decision.

“JB”, a married, 38-year-old mother of two, said: “I’m not necessarily going to get breast cancer, but if it can prevent it, I would be willing to take it, definitely.

“Obviously I’ve got young children to think about now. I would be happy to start taking it, but yes, I do look at the side effects.”

But another woman, “YN”, aged 59, who recently took responsibility for her parents’ care as well as that of her children, said, “in the short-term I just can’t cope [with the side effects]”.

Several respondents felt that medications were against their philosophy, while others looked at family and friends’ experiences of the drug which weren’t always successful.

“LL” a 47-year-old woman without children, whose mother died of breast cancer when she was eight, said she had always expected to face the disease at some point.

She told researchers: “It’s kind of written in the stars – that it’s my fate. So, what then would have been the point of any breast cancer prevention?”

There was no evidence that social factors, like ethnicity and educational attainment were having an impact on care choices, something lead researcher Dr Samuel Smith said was “reassuring”.

But he added: “its important doctors can discuss women’s concerns and provide information to help them while they are considering their options”.

Hundreds of thousands of women are offered Tamoxifen each year since the decision, hailed as a “game-changer” five years ago, to offer the option of the once-daily pill for prevention.

For the study, funded by Cancer Research UK and published in Breast Cancer Research and Treatment today, women at cancer centres in England were asked to complete a survey on their treatment decisions.

Of 258 women who responded to a three-month follow-up survey just 32 took up the offer of Tamoxifen, which has historically been used after cancer treatment to prevent tumours returning.


The drug selectively blocks oestrogen’s effects in breast tissue – oestroen is the hormone is responsible for the development of female physical traits but also increases the growth of cancer cells.

While taking Tamoxifen reduces the risk of osteoporosis – a weakening of the bones – it has other side-effects.

These include vaginal dryness, mood swings and irregular periods, there is also a small increase in the risk of developing blood clots and cancer of the uterus.

“While it is vital women with a high risk of breast cancer are offered Tamoxifen, there is a bigger, more complex picture,” said Carolyn Rogers, clinical nurse specialist at Breast Cancer Care.

“We know the drug may help reduce risk but it also comes hand-in-hand with side-effects, including menopausal symptoms like hot flushes and low libido, which can severely disrupt day-to-day life.

Risk-reducing surgery – such as a mastectomy – or regular screening could be more practical and preferable for some women, she added.

From Independent

Wow! I am Sure You Don’t Know this-Eating pasta 3 times a week won’t make you gain weight, according to a new study, it could even help you lose it


Low-carb diets, such as the Whole30 and Keto diet, are fiercely popular, and many people assume you should avoid eating too much pasta — along with other refined carbs — if you want to lose weight. Continue reading Wow! I am Sure You Don’t Know this-Eating pasta 3 times a week won’t make you gain weight, according to a new study, it could even help you lose it

Specific Type Of Blood Pressure Drug Increases Risk Of Pancreatic Cancer In Postmenopausal Women



A specific class of blood pressure medication is found to increase the pancreatic cancer risk in women, according to the AACR 2018 meeting on Tuesday. Continue reading Specific Type Of Blood Pressure Drug Increases Risk Of Pancreatic Cancer In Postmenopausal Women

The Menopause-Alzheimer’s Connection

In the next three minutes, three people will develop Alzheimer’s disease. Two of them will be women.

There are 5.7 million Alzheimer’s patients in the United States. By 2050, there will probably be as many as 14 million, and twice as many women as men will have the disease. Continue reading The Menopause-Alzheimer’s Connection

Allergan Weighs Options for Women’s Health Unit

Allergan Plc, which has been looking for ways to counter its stock slump as new threats to its top-selling skin and eye drugs have emerged, is considering options for its women’s health unit, according to people with knowledge of the matter. Continue reading Allergan Weighs Options for Women’s Health Unit